Cortison bei Hashimoto
Verfasst: 07 Nov 2021 13:02
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078294/
Medicine (Baltimore). 2021 Apr 23; 100(16): e25554.
Published online 2021 Apr 23. doi: 10.1097/MD.0000000000025554
PMCID: PMC8078294
PMID: 33879707
Glucocorticoid supplementation improves reproductive outcomes in infertile women with antithyroid autoimmunity undergoing ART
A meta-analysis
Guangqin Zhou, MD, Meiying Zhou, MD, Xuan Duan, MD, and Weihong Li, MD∗
Monitoring Editor: Saeed Marzoq Baradwan.
Author information Article notes Copyright and License information Disclaimer
Results:
Three publications with 237 antithyroid antibody (ATA)-positive and 384 ATA-negative women were included in the final analysis. Overall, glucocorticoid therapy showed satisfying effects on improving clinical pregnancy rate (OR = 4.63, 95% CI [2.23, 9.58], I2 = 0.0%, P < .0001) and live birth rate (OR = 3.19, 95% CI [1.13, 9.04], I2 = 0.0%, P = .03) of ATA-positive women compared with control group. However, it seems that glucocorticoid showed no significant difference in the abortion rate (OR = 0.62, 95% CI [0.09, 4.32], I2 = 35%, P = .64) and oocyte recovery (OR = 2.26, 95% CI [−1.46, 5.99], I2 = 79%, P < .0001) between the 2 groups.
Zusammenfassung:
Metaanalyse von 3 Studien
Glukokortikoide verbessern bei Hashi bei Art (assisted reproductive treatment) Patientinnen die Schwangerschaftsrate und Lebendgeburtenrate.
Sie schreiben, dass es keine Auswirkung bei den klinischen Schwangerschaften hat. Imho ist die Fallzahl für letzter Aussage zu gering
Medicine (Baltimore). 2021 Apr 23; 100(16): e25554.
Published online 2021 Apr 23. doi: 10.1097/MD.0000000000025554
PMCID: PMC8078294
PMID: 33879707
Glucocorticoid supplementation improves reproductive outcomes in infertile women with antithyroid autoimmunity undergoing ART
A meta-analysis
Guangqin Zhou, MD, Meiying Zhou, MD, Xuan Duan, MD, and Weihong Li, MD∗
Monitoring Editor: Saeed Marzoq Baradwan.
Author information Article notes Copyright and License information Disclaimer
Results:
Three publications with 237 antithyroid antibody (ATA)-positive and 384 ATA-negative women were included in the final analysis. Overall, glucocorticoid therapy showed satisfying effects on improving clinical pregnancy rate (OR = 4.63, 95% CI [2.23, 9.58], I2 = 0.0%, P < .0001) and live birth rate (OR = 3.19, 95% CI [1.13, 9.04], I2 = 0.0%, P = .03) of ATA-positive women compared with control group. However, it seems that glucocorticoid showed no significant difference in the abortion rate (OR = 0.62, 95% CI [0.09, 4.32], I2 = 35%, P = .64) and oocyte recovery (OR = 2.26, 95% CI [−1.46, 5.99], I2 = 79%, P < .0001) between the 2 groups.
Zusammenfassung:
Metaanalyse von 3 Studien
Glukokortikoide verbessern bei Hashi bei Art (assisted reproductive treatment) Patientinnen die Schwangerschaftsrate und Lebendgeburtenrate.
Sie schreiben, dass es keine Auswirkung bei den klinischen Schwangerschaften hat. Imho ist die Fallzahl für letzter Aussage zu gering