Verfasst: 04 Mär 2015 15:29
[quote="Else13"]Ich bin überhaupt kein Gegner von Dexa, ganz im Gegenteil. Aber bitte vorsichtig sein damit, gerade nach pos. Test. Ich wollte es jetzt eigentlich auch gerne haben, aber mein Arzt lässt sich nicht überreden, obwohl ich ihm Studien vorgelegt habe. Ich hätte sogar nach pos. Test wieder zu Predni gewechselt, wie es Dr. Beer vorschlägt.
-->nicht ganz, ich gehöre ja auch leider zu denen wie diese Frau hier unten die mit Beer gechattet hat. Denn auch ich habe immer wenn ein Embryo zu sehen war diese subchorialen Hämatome gehabt, genau wie sie auch immer in der 6. ssw! Beer hat zu Prednisolon gewechselt, wenn er über 2mg hinaus Kortison geben musste, denn die Hämatome sind ein Zeichen einer Falschen Immunantwort, so Beer. Hier also die Geschichte:
I will explain my situation and maybe Dr Beer can tell us the reasoning behind the different prescriptions? I am Category 1, 2, 3, 4, 5. I cannot do IVIg (IgA deficiency) and chose not to take Humira. I was on dexamethasone 1mg daily while trying to conceive from CD6. I got pregnant and continued the dexamethasone. Around 5 weeks we increased to twice daily because of my history of subchorionic hemorrhage. At 6 weeks US there was a possible hemorrhage, and Dr Beer switched me to 10mg prednisone twice daily - which I am still on, and the subchorioninc hemorrhage has disappeared at 9 weeks. So something has worked! My question: why the switch from dexamethasone to prednisone when all the literature says dexamethasone and prednisone are the same?
Answer: Dexamethasone and prednisone are not the same. Dexamethasone, not prednisone can prevent cell division of NK cells. Both calm inflammation produced by category 2 qand 3 immune problems. Prednisone can in my experience be given for a longer period during a pregnancy and data shows that women who take extra calcium do well without any bone side effects. With doses of over 20 mg a day prednisone increases the risk of gestational diabetes and screening for this condition. is necessary.
Question: There must be some differences? Just curious about it - and alot of other women are too, from the amount of discussion on it.
Answer: There are differences. I like dexamethasone better pre pregnancy and during early pregnancy because it also suppresses NK cells and reduces the need for Humira and IVIG. Your case is an example. In patients like you I find the risk of problems returning between 18 and 22 weeks and this involves slowing of the growth of the baby and shrinking of the amniotic fluid. This is why I do frequent ultrasound examinations in all of my patients taking immune medications.
Alan E Beer, MD
-->nicht ganz, ich gehöre ja auch leider zu denen wie diese Frau hier unten die mit Beer gechattet hat. Denn auch ich habe immer wenn ein Embryo zu sehen war diese subchorialen Hämatome gehabt, genau wie sie auch immer in der 6. ssw! Beer hat zu Prednisolon gewechselt, wenn er über 2mg hinaus Kortison geben musste, denn die Hämatome sind ein Zeichen einer Falschen Immunantwort, so Beer. Hier also die Geschichte:
I will explain my situation and maybe Dr Beer can tell us the reasoning behind the different prescriptions? I am Category 1, 2, 3, 4, 5. I cannot do IVIg (IgA deficiency) and chose not to take Humira. I was on dexamethasone 1mg daily while trying to conceive from CD6. I got pregnant and continued the dexamethasone. Around 5 weeks we increased to twice daily because of my history of subchorionic hemorrhage. At 6 weeks US there was a possible hemorrhage, and Dr Beer switched me to 10mg prednisone twice daily - which I am still on, and the subchorioninc hemorrhage has disappeared at 9 weeks. So something has worked! My question: why the switch from dexamethasone to prednisone when all the literature says dexamethasone and prednisone are the same?
Answer: Dexamethasone and prednisone are not the same. Dexamethasone, not prednisone can prevent cell division of NK cells. Both calm inflammation produced by category 2 qand 3 immune problems. Prednisone can in my experience be given for a longer period during a pregnancy and data shows that women who take extra calcium do well without any bone side effects. With doses of over 20 mg a day prednisone increases the risk of gestational diabetes and screening for this condition. is necessary.
Question: There must be some differences? Just curious about it - and alot of other women are too, from the amount of discussion on it.
Answer: There are differences. I like dexamethasone better pre pregnancy and during early pregnancy because it also suppresses NK cells and reduces the need for Humira and IVIG. Your case is an example. In patients like you I find the risk of problems returning between 18 and 22 weeks and this involves slowing of the growth of the baby and shrinking of the amniotic fluid. This is why I do frequent ultrasound examinations in all of my patients taking immune medications.
Alan E Beer, MD
